Flavonols act as antioxidants providing anti-inflammatory and anti-microbial benefits. Specifically, they have been found to arrest cell cycles as well as inhibit growth and spread of breast cancer cells in laboratory studies. Flavonols also directly support apoptosis (Lea MA, 2015).
Flavonols are found in fruits, vegetables, beans, peas and lentils are important anticancer nutrients. Flavonols from foods rather than supplements are more effective. Healthy levels of gut flora help us digest these nutrients whether from food or supplements.
Quercetin is a major flavonoid compound with potential anti-metastatic effects as it has been found to inhibit the invasion and migration of cancer cells in stress-related breast cancer. Quercetin may function by controlling signaling of adrenaline and noradrenaline, which are released from the adrenal glands during exposure to stress. Quercetin supplements are recommended during healing phases. Food sources are a sufficient source of quercetin during remission and include apples and onions.
Ellagic acid, is a dietary flavonoid polyphenol, which is present in abundance in pomegranate, muscadine grapes, walnuts and strawberries, has been shown to inhibit proliferation and induce apoptosis in breast cancer cells (Chen, 2015).